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Trivarol ampoule

Company name: Memphis co. for Pharm. & chem. Ind.

Trade name: Trivarol ampoule

Ampoule A:
Each 1 ml contains:
Thiamine hydrochloride (Vitamin B1)        100 mg
Pyridoxine hydrochloride (Vitamin B6)      25 mg
Sodium acid phosphate, sodium versenate, thiourea.

Ampoule B:
Each 1 ml contains:
Cyanocobalamine (Vitamin B12)                1 mg
Citric acid monohydrate, dibasic sodium phosphate anhydrous, probyl paraben base.
Pharmaceutical form: ampoules.

Pharmacological action:
Vitamin B1 combines with ATP (Adenosine triphosphate) to form thiamine pyrophosphate, also known as co-carboxylase, a co-enzyme, which catalyzes the decarboxylation of pyruvic acid and other keto acids.
Vitamin B6 acts as a co-enzyme in the metabolism of proteins, carbohydrates and fats. It participates in the decarboxylation and transamination of amino acids and is responsible for the breakdown of glycogen to glucose 1-phosphate.
Vitamin B12 is essential for growth, cell reproduction, hematopoiesis and synthesis of nucleoprotein and myelin.

Trivarol ampoule is indicated in painful neuritis, inborn errors of metabolism, inadequate dietary intake, pernicious anemia, hemolytic anemia, cases of increased vitamin requirement such as pregnancy.

Dosage & administration:

One ampoule (A+B) daily or as prescribed by the physician.

Mode of use:

Withdraw the contents of both ampoules into the same syringe and inject IM.

A history of sensitivity to any component of the product.

Side effects:
- Mild transient diarrhea and itching are reported.
- Feeling of warmth, tightness of throat, nausea and headache.

Drug interactions:
-    Vitamin B6 increases the peripheral metabolism of levodopa.
-    Chloramphenicol may antagonize the hematopoietic response to vitamin B12.
-    Colchicine, aminoglycosides, certain anticonvulsants e.g. (phenytoin, Phenobarbital) and para aminosalicylic acid may impair the absorption of vitamin B12.

Therapeutic category: Multivitamins.

Legal category: OTC.



Medicament is a product, which affects your health and its consumption contrary to instructions is dangerous for you. Follow strictly the doctor’s prescription, the method of use and the instructions of the pharmacist who sold the medicament.
- The doctor and the pharmacist are the experts in medicines, their benefits and risks.
- Do not by yourself interrupt the period of treatment prescribed.
- Do not repeat the same prescription without consulting your doctor.
- Keep all medicaments out of reach of children.

Council of Arab Health Ministers, Union of Arab Pharmacists.