Company name: Memphis co. for Pharm. & Chem. Ind.

Trade name: Relaxine tablet

Generic name: Thiocolchicoside

Each tablet contains:
Thiocolchicoside                      4 mg

Talc, sucrose, starch, lactose, gelatin, magnesium stearate.

Pharmaceutical form: tablets

Pharmacological actions:
Muscle relaxant:
- Relaxine tablet removes or significantly reduces muscle spasm (contraction) of central origin: in case of spastic hypertonia, it decreases passive resistance of the stretched muscle and reduces the remaining spasm, it acts through the intermediary of the CNS and not by the paralysis of the neuromuscular junction that acts.
- Its action as myorelaxant is also manifested on visceral muscles especially uterus.
- Relaxine tablet has selective affinity to GABA receptors and also has the properties of glycinergic agonists, it doesn't act on voluntary muscles so it doesn't influence respiratory system and also the cardiovascular system.

After oral administration, Peak plasma concentrations are observed after 50 min.
- Elimination half life is 4.5 hours.
- Thiocolchicoside is eliminated at the same time through renal way without any change and by extra renal way.

Supplementary treatment of painful muscle contractions.

Dosage and administration:

Adults above 15 years: 4 tablets daily in divided doses.
The tablets should be taken with a full glass of water.

Relaxine tablet is contraindicated in patients with known hypersensitivity to thiocolchicoside or to any of its components or to colchicines.

Side effects:
- Rare cases of hypersensitivity as urticaria, edema, and anaphylactic shock, digestive troubles such as gastralgia and diarrhea.
- Very rare cases of erythema, maculopapular eruptions and vesiculo- papular eruptions.

The use of Relaxine is not recommended during first trimester.

Relaxine is contraindicated during lactation.

Warnings and precautions:
- Relaxine tablet should be taken with caution for epileptic patients or with patients at risk of convulsions.

- The dose should be reduced in case of diarrhea.

- Since the drug contains sucrose and lactose, Relaxine is contraindicated in case of congenital galactosemia, fructose intolerance, malabsorption syndrome of glucose and galactose, deficiency in lactase and sucrose iso–maltase. And in diabetic patients.

Therapeutic category: Muscle relaxant.

Legal category: POM.


Medicament is a product, which affects your health and its consumption contrary to instructions is dangerous for you.Follow strictly the doctor’s prescription, the method of use and the instructions of the pharmacist who sold the medicament.
- The doctor and the pharmacist are the experts in medicines, their benefits and risks.
- Do not by yourself interrupt the period of treatment prescribed.
- Do not repeat the same prescription without consulting your doctor.
- Keep all medicaments out of reach of children.

Council of Arab Health Ministers, Union of Arab Pharmacists.