Industries. TRADE NAME: Glycerol Suppositories B.P. 2022. GENERIC NAME: glycerol. COMPOSITION: Each suppository contains : Active ingredient: Glycerol 1.61 gm : Excipients Gelatin, water. PHARMACEUTICAL FORM: Rectal suppositories. PHARMACOLOGICAL ACTION: PHARMACODYNAMICS: Glycerol by the rectal route promotes peristalsis and evacuation of the lower bowel by virtue of its irritant action. PHARMACOKINETICS: No information has been found on the pharmacokinetics of glycerol administered rectally. INDICATIONS: For the relief of occasional constipation. DOSAGE AND ADMINISTRATION: Method of administration: Rectal. One suppository as required. The suppository should be dipped in water before insertion. The suppositories are defined as adult size, therefore there is no children’s use recommendation. They are suitable for use by the elderly, dose and dosage schedule as above. CONTRAINDICATIONS: Contra-indicated in patients with known hypersensitivity to glycerol . It is also contraindicated in GIT obstruction. Adult suppositories are not suitable for use by children and infants. UNDESIRABLE EFFECTS: Gastrointestinal Disorders: May cause irritation and occasionally abdominal cramps. Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via
